Want to volunteer to participate in a current or future clinical trial to study the safety and effectiveness of COVID-19 vaccines and antibodies? Here’s your chance. The National Institute of Allergy and Infectious Diseases (NIAID) has established the COVID-19 Prevention Trials Network (CoVPN) to test a variety of investigational vaccines and monoclonal antibodies against the novel coronavirus.

The CoVPN is part of “Operation Warp Speed,” a partnership launched by the Department of Health and Human Services (HHS) to expedite the development, manufacturing, and distribution of vaccines, therapeutics, and diagnostics for COVID-19 in the wake of the global pandemic. The network was formed from four existing NIAID-funded clinical trial networks:

  • HIV Vaccine Trials Network (HVTN) based in Seattle;
  • HIV Prevention Trials Network (HPTN) based in Durham, North Carolina;
  • Infectious Diseases Clinical Research Consortium (IDCRC) based in Atlanta;
  • AIDS Clinical Trials Group based in Los Angeles.

CoVPN is kicking into high speed and engaging communities to recruit thousands of volunteers to participate in late-stage clinical trials of COVID-19 vaccines. The trials will take place at more than 100 sites across the U.S. and the world. Approximately 30,000 participants are needed. The mRNA-1273 vaccine (Moderna) will be the first to be evaluated. The primary endpoint is to prevent symptomatic COVID-19. The secondary endpoints include prevention of severe COVID-19 and prevention of COVID-19-related infection by severe acute respiratory syndrome.

“Having a safe and effective medical countermeasure to prevent COVID-19 would enable us to not only save lives but also help end the global pandemic,” said NIAID Director Anthony S. Fauci, MD. “Centralizing our clinical research efforts into a single trials network will expand the resources and expertise needed to efficiently identify safe and effective vaccines and other prevention strategies against COVID-19.”

Those interested in volunteering for the study can apply to the CoVPN Volunteer Screening Registry. Participants must be 18 years or older and must complete a short online survey that includes some personal questions. For more information, visit the COVID-19 Prevention Network.

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