Pfizer Inc. said Friday it has found an increased risk of heart problems with patients taking its painkiller Celebrex, a drug that is in the same class as the Vioxx, which was pulled from the market in September because of safety concerns.

Pfizer said the increased risk was found in one of two long-term cancer prevention trials, while the other trial showed no increased risk.

The National Cancer Institute, which was conducting the study for Pfizer, suspended the use of Celebrex after finding that patients taking 400mg to 800mg of the drug daily were found to have a risk of 2.5 times greater of experiencing heart problems than those who weren’t. A separate cancer study found no increased heart risk with patients taking 400mg of Celebrex per day.

Pfizer was conducting the trials as part of an effort to find a new application for the drug.

The news sent the stock of the giant pharmaceutical maker plunging in early trading on the New York Stock Exchange, where its shares were down $5.61, or more than 19 percent, at $23.37.

Both Celebrex and Vioxx, which is made by Merck & Co., are a type of drug called cox-2 inhibitors, which have become popular because of their effectiveness in treating the pain of arthritis and other ailments.

Earlier this month, the Food and Drug Administration said it was adding a warning to the labels of another Pfizer drug, Bextra, warning of potential heart problems associated with the use of Bextra in people who have recently had heart bypass surgery. Bextra is also a cox-2 inhibitor type of drug.

Celebrex is currently approved for use in the United States for the treatment of arthritis and pain. Users should consult their physicians before making decisions about discontinuing its use.



We're here to help!

We live by our creed of “helping those who need it most” and have helped thousands of clients get the justice they desperately needed and deserved. If you feel you have a case or just have questions please contact us for a free consultation. There is no risk and no fees unless we win for you.

Fields marked * may be required for submission.


Beasley Allen Law Firm
What is Celebrex? Celebrex is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs)....

Lawyers and staff continue to help me

I suffered from an allergic reaction to a common medication causing permanent injury when I was 15 years old. My settlement allows me to take care of myself instead of being on disability. Even after my case was over, the lawyers and staff continue to help me.

—Tamika