New York, NY – A phase III clinical trial is underway, in Maryland, at the National Institutes of Health Clinical Center, to determine how effective vorinostat is at treating patients with pleural malignant mesothelioma. Research is underway specifically about Vorinostat, also known as suberoylanilide hydroxamic acid, is marketed under the brand name Zolinza.

This mesothelioma clinical trial will try to ascertain the level of toxicity as well as any side effects that are occasioned in patients who have been prescribed Vorinostat (Zolinza) and to compare these results against those of patients who have been administered a placebo.

The title for this ongoing project is "A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Oral Suberoylanilide Hydroxamic Acid (L-001079038) in Patients With Advanced Malignant Pleural Mesothelioma Previously Treated With Systemic Chemotherapy " Raffit Hassan, MD, is the protocol chair for this study. The expected enrollment for the mesothelioma clinical trial study is 660 mesothelioma patients.

All patients in this malignant mesothelioma research study must have a histologically or cytologically confirmed diagnosis of pleural mesothelioma, which may be of the epithelial, sarcomatoid or mixed sub-type. All patients must also have previously gone through 1 or 2 standard systemic mesothelioma treatments that included pemetrexed disodium and either cisplatin or carboplatin. Researches on behalf of the mesothelioma clinical trial hope for some positive results and low side effects in the trial study of Vorinostat.

For more information on this clinical trial for mesothelioma please visit National Cancer Institute's webpage.

Asbestos is the only known cause of mesothelioma, a terminal form of cancer that develops primarily in the lining of the lungs and the abdomen. Research into malignant mesothelioma has shown that mesothelioma generally occurs at least fifteen years after the initial exposure to asbestos. Asbestos can cause mesothelioma even when the exposure occurs for a short duration. Asbestos fibers are microscopic and exposure can occur without a worker even knowing it. Mesothelioma occurs not only in people working directly with asbestos products but also in bystanders and family members exposed to asbestos dust.

 



We're here to help!

We live by our creed of "helping those who need it most" and have helped thousands of clients get the justice they desperately needed and deserved. If you feel you have a case or just have questions please contact us for a free consultation. There is no risk and no fees unless we win for you.

Fields marked    may be required for submission.
  1. I'm an attorney

Ban Asbestos Now Act of 2017 proposed in Senate

At the end of October, the Environmental Protection Agency (EPA) announced it would be adjusting the...

EPA limits reach of toxic chemical evaluations

The EPA is reneging on promises to evaluate some of the most dangerous chemicals used by the public,...

Prevention remains the only way to end mesothelioma...

Mesothelioma is a deadly cancer that can affect the lining of the heart, the lining of the abdomen or,...

Controversial FACT Act headed to House floor for vote

The Furthering Asbestos Claim Transparency Act of 2017 (FACT Act) or H.R. 906, uses the guise of...
asbestos dust hazard perimeter tape

Canada joins countries implementing asbestos bans

Asbestos, a group of fibrous silicate minerals, is a known carcinogen and is closely linked to the...

Asbestos in schools poses mesothelioma risk. Who is...

According to the Environmental Protection Agency (EPA), approximately 15 million students and 1.4...

Excellent law firm

Beasley Allen is an excellent law firm. I highly recommend their services.

—William M.