CHICAGO (Reuters) – Drugmaker Merck & Co. on Wednesday gave preliminary results of a study of its
investigation of painkiller Arcoxia, the planned successor to Vioxx, which was pulled off the market in 2004 after being linked to stroke and heart attack.

Merck said the study, comparing Arcoxia with the anti-inflammatory drug diclofenac, found the “relative risk” of certain cardiovascular events was similar.

The incidence of patients withdrawing from the study due to side effects related to high blood pressure, edema and congestive heart failure was significantly higher for Arcoxia than for diclofenac, it said.

The U.S. Food and Drug Administration, rather than approve the Arcoxia outright, had sent Merck an “approvable letter” seeking more information on the drug.

Vioxx was pulled off the market in 2004 after findings that it doubled the risk of heart attack and stroke, leading Merck shares to sink and resulting in thousands of lawsuits against the company.



We're here to help!

We live by our creed of “helping those who need it most” and have helped thousands of clients get the justice they desperately needed and deserved. If you feel you have a case or just have questions please contact us for a free consultation. There is no risk and no fees unless we win for you.

Fields marked * may be required for submission.


Continuing the battle with Big Pharma

The entire Beasley Allen staff had our personal interest at heart. We were part of the family of a down to earth, trustworthy, understanding law firm. Thank you, Beasley Allen, for continuing the battle with Big Pharma.

—Richard