Think generic medications are just the same as their brand name equivalents? Think again. Generics may be less expensive – a benefit for insurance providers as well as consumers – but for some, that savings may come at a price. Just ask Beverly*, who wrote to the People’s Pharmacy about the anti-seizure and bipolar drug Lamictal. The clinical nurse specialist who is also a midlevel prescriber said she has submitted 37 adverse-event reports to the Food and Drug Administration’s MedWatch program about the generic version of Lamictal, known as lamotrigine.

“Most of the adverse events involved a loss of response, but many involved a loss of response and additional side effects that did not occur with brand-name Lamictal,” Beverly told People’s Pharmacy. “When a generic for Lamictal first came on the market I was enthusiastic since I knew my patients would be paying less. But after so many patients had serious relapses of their mood disorders with generic lamotrigine formulations, I am no longer enthusiastic.”

People’s Pharmacy responded that they had received other complaints about generic Lamictal, as well as another anti-epilepsy medication, levetiracetam, known by the brand name Keppra.

While the FDA reviews generic drugs to ensure the active ingredients are equivalent, oftentimes the inactive ingredients between brand names and their generic equivalents differ. This subtle difference rarely causes problems for the general public, but some researchers say that consumers with neurological problems, such as epilepsy, may be more sensitive and experience breakthrough seizures and other side effects with switching from a brand name medication to a generic one.

While switching to a generic medication may save consumers money, experts urge neurological patients taking anti-epileptic medication to discus their condition with their health care professional before switching from a brand name to a generic or from one generic to another.



We're here to help!

We live by our creed of “helping those who need it most” and have helped thousands of clients get the justice they desperately needed and deserved. If you feel you have a case or just have questions please contact us for a free consultation. There is no risk and no fees unless we win for you.

Fields marked * may be required for submission.


Professional and appropriate manner

My claim was handled in a very professional and appropriate manner. I was very pleased with my outcome and that the claim was resolved without having to go through a trial.

—Michael